Hyaluronic acid (HA) is widely used for numerous medical applications, such as
viscosupplementation, eye surgery and drug delivery. A broad range of HA-based materials have …

Gene delivery is too complex to be performed with a single carrier molecule. Synthetic
multicomponent vectors are being designed that mimic key properties of viruses. Some solutions, …

Micro-computed tomography (micro-CT) is an X-ray based instrument that it is specifically
designed for biomedical research at a preclinical stage for live imaging of small animals. This …

Small interfering RNAs offer novel opportunities to inhibit gene expression in a highly selective
and efficient manner but depend on cytosolic translocation with synthetic delivery systems…

The bleomycins (BLM) are a family of clinically used antitumor antibiotics. 1 Their mechanism
of action is believed to involve the degradation of DNA2 and possibly of RNA. 3 BLM-…

Using a dissymmetrically-perturbed particle-in-a-box model, we demonstrate that the
induced optical activity of chiral monolayer protected clusters, such as Whetten’s Au28(SG)16 …

Objective To evaluate whether miR-20a belonging to the cluster miR-17–92 is a negative
regulator of inflammation in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) by …

A defined medium was developed which, by means of a specific fed-batch mode, allows
growth of the recombinant Escherichia coli strain TG1 (pBB210) up to a cell density of 60 g dry …

… p-type functions on hydrogen atoms to the 3-21++G 26 and the STO-3++G set, the latter
related to STO-3G in the same way as 3-21++G is to 3-21G. DP stands for diffuse polarization …

Recombinant proteins with cytosolic or nuclear activities are emerging as tools for interfering
with cellular functions. Because such tools rely on vehicles for crossing the plasma …