Background Human genetics research lacks diversity; over 80% of genome‐wide association
studies have been conducted on individuals of European ancestry. In addition to limiting …

The clinical and commercial success of covalent drugs has prompted a renewed and more
deliberate pursuit of covalent and irreversible mechanisms within drug discovery. A covalent …

Background Knowledge regarding the modifiable risk factors of dementia is fundamental to
guide public health policy. We aimed to estimate the population attributable fraction of …

Compounds that exhibit assay interference or undesirable mechanisms of bioactivity ("nuisance
compounds") are routinely encountered in cellular assays, including phenotypic and …

The article discusses the pilot implementation of the evidence-based preventive program
Good Behavior Game (GBG) in public schools in four Brazilian cities. GBG is a method for …

… μM to 0.001 μM). After a 10-min incubation, erythropoietin (1.6 units/ml) (R&D Systems,
Minneapolis, MN, USA) was added for 20 min, then the cells were fixed, incubated with Mouse-…

Objective To compare the efficacy of priming the uterine cervix before Manual Vaccum
Aspiration (MVA) using 200 µg or 400 µg of vaginal misoprostol, inserted a mean time of 6 h …

Usually the separation of CO 2 from the flue gas in power plants is connected with high
efficiency losses, independent of separation technology. The reason is that the separation …

We present a numerical algorithm for the simulation of resonant x-ray magnetic scattering in
reflection geometry for an arbitrary three-dimensional magnetization distribution over a …

Conclusions: Amantadine is an antiparkinsonian medication scarcely associated with PHS.
The few reported cases are further summarized and discussed in this article. This case …