… of high titres of NAbs — a robust cytotoxic CD8 + T cell response and a T H 1 cell-biased
CD4 + T cell effector response would result in protective immunity against COVID-19 (ref. ). …

Given the "inborn" nature of the innate immune system, it is surprising to find that innate
immune function does in fact change with age. Similar patterns of distinct Toll-like-receptor-…

Infections in the first year of life are common and often severe. The newborn host demonstrates
both quantitative and qualitative differences to the adult in nearly all aspects of immunity, …

Asthma is the most prevalent pediatric chronic disease and affects more than 300 million
people worldwide. Recent evidence in mice has identified a “critical window” early in life where …

The global pandemic of COVID-19 cases caused by infection with SARS-CoV-2 is ongoing,
with no approved antiviral intervention. We describe here the effects of treatment with …

A fundamental tenet of scientific research is that published results are open to independent
validation and refutation. Minimum data standards aid data providers, users, and publishers …

Importance Global use of human papillomavirus (HPV) vaccines to prevent cervical cancer
is impeded by cost. A 2-dose schedule for girls may be possible. Objective To determine …

The human neonate and infant are unduly susceptible to infection with a wide variety of
microbes. This susceptibility is thought to reflect differences from adults in innate and adaptive …

Drawing on previous literature proposing that entrepreneurial orientation (EO) reflects a
disposition toward, rather than actual involvement in, entrepreneurial activity, and on the …

OBJECTIVE. The objective of our study was to perform a meta-analysis to evaluate the
diagnostic performance of low-dose CT for the diagnosis of urolithiasis (seven studies, 1,061 …