PT - JOURNAL ARTICLE AU - Patrick O'Hagan TI - Orphan Drug Act AID - 10.3905/jpe.2001.319993 DP - 2001 Aug 31 TA - The Journal of Private Equity PG - 14--30 VI - 4 IP - 4 4099 - https://pm-research.com/content/4/4/14.short 4100 - https://pm-research.com/content/4/4/14.full AB - Orphan drug companies sit at the intersection of the public and private sectors, as various regulatory agencies and nonprofit organizations join to encourage the development of new treatments for rare diseases—about 6,000 mostly genetic ailments that, in sum, affect roughly one in ten Americans, or close to 25 million people. Congressional approval of the Orphan Drug Act (ODA) in 1983, and subsequent cooperation between a number of public and private institutions, have created more attractive protections and incentives for venture capital and private equity firms to invest in drug development targeted at “orphan diseases.”