Cardiovascular optical coherence tomography (OCT) is a catheter-based invasive imaging
system. Using light rather than ultrasound, OCT produces high-resolution in vivo images of …

Next is a granulation or cellular proliferation phase. Growth factors are subsequently released
from platelets, leukocytes, and SMCs, which stimulate migration of SMCs from the media …

Background Angiotensin-receptor blockers (ARBs) are a widely used drug class approved
for treatment of hypertension, heart failure, diabetic nephropathy, and, recently, for …

Background Dual antiplatelet therapy is recommended after coronary stenting to prevent
thrombotic complications, yet the benefits and risks of treatment beyond 1 year are uncertain. …

Endothelium-derived relaxing factor (EDRF) activity has been attributed to the highly labile
nitric oxide radical (NO). In view of the fact that the plasma and cellular milieux contain …

… of stoichiometric concentrations of S-nitrosoglutathione, measured as acid- or acetone-soluble
S-nitrosothiol by the photolysis-chemiluminescence method described here or directly by …

Textbooks often portray thrombosis as a bland protec-tive mechanism critical for stanching
blood loss after injury: the prick of a lancet, the wound of a scalpel, or the predator’s fangs …

Integrin function is central to inflammation, immunity, and tumor progression. The urokinase-type
plasminogen activator receptor (uPAR) and integrins formed stable complexes that both …

… Simon, Harold A. Chapman, and Peter Libby … Simon (HL/DK57506) supported this work.
DI Simon is the recipient of grant-in-aid #13-526-945 from the American Heart Association, …

The vascular endothelium is a critical regulator of vascular function. Diverse stimuli such as
proinflammatory cytokines and hemodynamic forces modulate endothelial phenotype and …