… -based surveys for amoA indicated that archaeal ammonia oxidizers are widespread in
marine sponges (D. Steger et al., unpublished data). Whether archaea or bacteria are the key …

… Cells were grown in differentiation medium for 3 d, followed by 2 d in growth medium with
insulin, followed by growth medium only. 293T cells were grown in high-glucose DMEM (…

The histone H3 lysine 79 methyltransferase DOT1L/KMT4 can promote an oncogenic
pattern of gene expression through binding with several MLL fusion partners found in acute …

A number of transcriptional coactivator proteins have been identified as histone
acetyltransferase (HAT) proteins, providing a direct molecular basis for the coupling of histone …

… d, Transcription was assayed with nucleosomal templates as in a, including or omitting
acetyl CoA as indicated. SAGA or NuA4 stimulation of VP16-mediated transcription required …

… (D) Northern analysis ofpho81Δ pho80 ts strains with the relevant genotypes indicated.
PHO5 and PHO84 mRNA amounts in the plc1, arg82, ipk1, andkcs1 mutants were 6% and 77%, …

Activation of gene transcription in vivo is accompanied by an alteration of chromatin structure.
The specific binding of transcriptional activators disrupts nucleosomal arrays, suggesting …

… (C,D) Gene expression determined by qPCR after pretreatment with TSA in wild-type
macrophages (C) and HDAC3 knockout macrophages (D). (E) Gene expression determined by …

… (D) RORα binding at clock and control genes promoters at ZT10, in WT, Rev-erbα KO (αKO),
Rev-erbβ knockdown (βKD), and αKO/βKD mice liver, analyzed by ChIP-PCR. Data are …

Chromatin influences gene expression by restricting access of DNA binding proteins to their
cognate sites in the genome 1 , 2 , 3 . Large-scale characterization of nucleosome …