We have carried out a multi-disciplinary study of the effects of prenatal protein malnutrition
on the developing rat brain. These experiments, involving anatomical, physiological, …

A sensitive micro-method specific for deoxyribonucleic acid was applied to brain. Samples
were treated with trichloroacetic acid and lipids were removed by extracting with alcoholic …

A total of 342 previously untreated eligible children were entered into the first Intergroup
Ewing's Sarcoma Study (IESS) between May 1973 and November 1978. In group I institutions, …

Two Pediatric Intergroup Ewing's Sarcoma studies of patients with metastatic disease (IESS‐MD)
have used multimodal therapy consisting of intensive combination chemotherapy and …

… A pathologist (J. Kissane) who was blind to the treatments examined and graded all the
specimens utilizing a scoring system described previously (18). The pathological …

The effects of administering insulin-like growth factor I (IGF-I) were examined in a model of
ischemic acute tubular necrosis in rats. Injury was induced by 75 min of bilateral renal artery …

… Stratton B, Askin FB, Kissane JM: Intramyofiber skeletal muscle invasion in Ewing's sarcoma
of bone: Clinicopathologic observations from the Intergroup Ewing'ssarcoma study. Am …

Ewing's sarcoma is a rare tumor of the bone. In the Intergroup Ewing's Sarcoma Study (IESS)
approximately 4% of the primary bone tumors arose in the bones of the head and neck. …

Use of β 2 microglobulin to diagnose tubulo-interstitial renal lesions in children. Fractional
excretion (FE) of β 2 microglobulin (β 2 M) was studied in children with glomerular (N = 114), …

Renal involvement in the tuberous sclerosis complex includes angiomyolipomas, cysts, and
carcinomas. Angiomyolipomas, despite a sometimes frightening histopathologic appearance…