Microglia states and nomenclature: A field at its crossroads
Microglial research has advanced considerably in recent decades yet has been constrained
by a rolling series of dichotomies such as "resting versus activated" and "M1 versus M2." …
by a rolling series of dichotomies such as "resting versus activated" and "M1 versus M2." …
Alternative activation of macrophages
S Gordon - Nature reviews immunology, 2003 - nature.com
The classical pathway of interferon-γ-dependent activation of macrophages by T helper 1 (T
H 1)-type responses is a well-established feature of cellular immunity to infection with …
H 1)-type responses is a well-established feature of cellular immunity to infection with …
Monocyte and macrophage heterogeneity
S Gordon, PR Taylor - Nature reviews immunology, 2005 - nature.com
Heterogeneity of the macrophage lineage has long been recognized and, in part, is a result
of the specialization of tissue macrophages in particular microenvironments. Circulating …
of the specialization of tissue macrophages in particular microenvironments. Circulating …
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
…, C Churcher, D Harris, SV Gordon, K Eiglmeier, S Gas… - Nature, 1998 - nature.com
As a result of an error during film output, Table 1 was published with some symbols missing.
The correct version can be found at http://www. sanger. ac. uk and is reproduced again here …
The correct version can be found at http://www. sanger. ac. uk and is reproduced again here …
[HTML][HTML] Macrophage activation and polarization: nomenclature and experimental guidelines
Description of macrophage activation is currently contentious and confusing. Like the biblical
Tower of Babel, macrophage activation encompasses a panoply of descriptors used in …
Tower of Babel, macrophage activation encompasses a panoply of descriptors used in …
Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU)
ContextDelirium is a common problem in the intensive care unit (ICU). Accurate diagnosis is
limited by the difficulty of communicating with mechanically ventilated patients and by lack …
limited by the difficulty of communicating with mechanically ventilated patients and by lack …
Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit
EW Ely, A Shintani, B Truman, T Speroff, SM Gordon… - Jama, 2004 - jamanetwork.com
ContextIn the intensive care unit (ICU), delirium is a common yet underdiagnosed form of
organ dysfunction, and its contribution to patient outcomes is unclear.ObjectiveTo determine if …
organ dysfunction, and its contribution to patient outcomes is unclear.ObjectiveTo determine if …
Genetic studies of body mass index yield new insights for obesity biology
…, B Gigante, AS Go, A Golay, AH Goodall, SD Gordon… - Nature, 2015 - nature.com
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta-…
obesity better, here we conduct a genome-wide association study and Metabochip meta-…
[HTML][HTML] Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C
JG McHutchison, SC Gordon, ER Schiff… - … England Journal of …, 1998 - Mass Medical Soc
Background Only 15 to 20 percent of patients with chronic hepatitis C have a sustained
virologic response to interferon therapy. We compared the efficacy and safety of recombinant …
virologic response to interferon therapy. We compared the efficacy and safety of recombinant …
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial
Background A sustained virological response (SVR) rate of 41% has been achieved with
interferon alfa-2b plus ribavirin therapy of chronic hepatitis C. In this randomised trial, …
interferon alfa-2b plus ribavirin therapy of chronic hepatitis C. In this randomised trial, …