Extracellular vesicles (EVs) are small, double membrane vesicles derived from leukocytes,
platelets, and cells of other tissues under physiological or pathological conditions. …

West Nile virus (WNV) causes asymptomatic infection in most humans, but for undefined
reasons, approximately 20% of immunocompetent individuals develop West Nile fever, a …

Objective: HIV+ elite controllers are a unique group of rare individuals who maintain undetectable
viral loads in the absence of antiretroviral therapy. We studied immune responses in …

Although cryopreservation of peripheral blood mononuclear cells (PBMC) is a commonly
used technique, the degree to which it affects subsequent functional studies has not been well …

In the Trial to Reduce Alloimmunization to Platelets (TRAP) study, 101 of 530 participants
became refractory to platelet transfusions without evidence of HLA or human platelet antigen (…

BACKGROUND: Trauma and transfusion can both alter immunity, and while transfusions are
common among traumatically injured patients, few studies have examined their combined …

A subset of HIV-infected individuals termed elite controllers (ECs) maintain CD4 + T cell
counts and control viral replication in the absence of antiretroviral therapy (ART). Systemic …

… It is concluded that the present study is the first to show that 10% (w/w) dietary pectin or guar
gum in the diet (when used as the sole fiber source during the promotional stage of carcino…

To understand how extracellular vesicle (EV) subtypes differentially activate monocytes, a
series of in vitro studies were performed. We found that plasma-EVs biased monocytes toward …

BACKGROUND: Donor white blood cells (WBCs) present in transfusion products can lead
to immune sequelae such as production of HLA antibodies or graft‐versus‐host disease in …